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CAS RN: 3768-18-1 | Product Number: A3535
N4-Acetylcytidine
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Purity: >95.0%(T)(HPLC)
Synonyms:
- N-(1,2-Dihydro-2-oxo-1-β-D-ribofuranosyl-4-pyrimidinyl)acetamide
- N-[1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl]acetamide
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
¥4,900
|
24 | 2 | Contact Us | |
| 25G |
¥16,800
|
19 | 3 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | A3535 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__5N__3O__6 = 285.26 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 3768-18-1 |
| Reaxys Registry Number | 624343 |
| MDL Number | MFCD00006540 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Specific rotation | +55.0 to +59.0 deg(C=1, water) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 209 °C |
GHS
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Application
N4-Acetylcytidine: A Highly Conserved Modified RNA nucleoside
N4-Acetylcytidine (ac4C) is a highly conserved modified RNA nucleoside whose formation is catalyzed by the N-acetyltransferase 10 (NAT10). Recent studies have discovered that N4-acetylcytidine is a prevalent mRNA modification in eukaryotes and has roles in cell viability and development through these effects on RNA as follows; translation efficiency, mRNA stability, codon recognition, and tRNA structure, thereby opening up an emerging research field known as epitranscriptomics.
References
- Acetylation of Cytidine in mRNA Promotes Translation Efficiency
- The Processing, Gene Regulation, Biological Functions, and Clinical Relevance of N4-Acetylcytidine on RNA: A Systematic Review
- The emerging role of RNA modifications in the regulation of mRNA stability (a review)
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