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CAS RN: 1134-47-0 | Product Number: B3343
Baclofen
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Purity: >98.0%(T)
Synonyms:
- 4-Amino-3-(4-chlorophenyl)butyric Acid
Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
More Stock Info
|
|---|---|---|---|---|---|
| 1G |
¥4,400
|
9 | |||
| 5G |
¥12,400
|
4 | 4 | ||
| 25G |
¥42,700
|
1 | 1 |
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* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
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* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* For the case that without specific estimated shipping data, e.g.: If displayed as "will be shipped after 8 working days", the products will be shipped 8 working days later after ordering.
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | B3343 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2ClNO__2 = 213.66 |
| Physical State (20 deg.C) | Solid |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1134-47-0 |
| Reaxys Registry Number | 2104494 |
| PubChem Substance ID | 87561134 |
| Merck Index (14) | 937 |
| MDL Number | MFCD00055143 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 208 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | MW5084200 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
Application
Baclofen: A γ-Amino Butyric Acid Type B (GABAB) Receptor Agonist
Baclofen is a γ-amino butyric acid type B (GABAB) receptor agonist. Baclofen is a muscle relaxant and antispastic, but the precise mechanism of action of baclofen is not fully understood. However, baclofen is a structural analog of the inhibitory neurotransmitter GABA, and may exert its effects by stimulating of the GABAB receptor subtype. Current studies suggest that baclofen may reduce alcohol dependence. Baclofen is a racemic compound, and its active enantiomer is (R)-Baclofen (l-baclofen or STX209) [B5102]. (The product is for research purpose only.)
References
- Baclofen. Preliminary report of its pharmacological properties and therapeutic efficacy in spasticity (a review)
- (-)-Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor
- A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system (a review)
- Baclofen: a new drug for the treatment of alcohol dependence (a review)
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