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CAS RN: 51333-22-3 | Product Number: B3909
Budesonide
×
Purity: >98.0%(HPLC)
Synonyms:
- (+)-16α,17α-Butylidenedioxy-11β,21-dihydroxy-1,4-pregnadiene-3,20-dione
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
¥9,100
|
≥40 | It can be shipped from Saitama warehouse on the same day* | It can be shipped in about 2 weeks after ordering | |
| 1G |
¥31,800
|
13 | 15 | 27 |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | B3909 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__4O__6 = 430.54 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 51333-22-3 |
| Reaxys Registry Number | 3633996 |
| PubChem Substance ID | 160871371 |
| Merck Index (14) | 1468 |
| MDL Number | MFCD00083259 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 % (total of isomers) |
| Elemental analysis(Carbon) | 68.00 to 71.00 % |
| Specific rotation [a]20/D | +100 to +110 deg(C=0.28、CH2Cl2) |
| NMR | confirm to structure |
Properties (reference)
| Specific Rotation | 105° (C=0.28,CH2Cl2) |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Chloroform, Methanol |
| Solubility (slightly sol. in) | Ethanol, Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | TU3723000 |
Transport Information:
Application
Budesonide: A Potent Glucocorticoid Receptor Antagonist
Budesonide is an anti-inflammatory corticosteroid that exhibits potent glucocorticoid activity and weak mineralocorticoid activity.1-6） Budesonide has a strong affinity for glucocorticoid receptor, and it is reported that budesonide has approximately 8.5-fold, 15-fold, and 195-fold greater than those of dexamethasone [D1961], prednisolone [P0637], and hydrocortisone [H0533], respectively.6) Budesonide is mainly metabolized by CYP3A4.6) (The product is for research purpose only.)
References
- 1)Scientific rationale for inhaled combination therapy with long-acting β2-agonists and corticosteroids(a review)
- 2)Budesonide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy in asthma and rhinitis(a review)
- 3)Budesonide: A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease(a review)
- 4)Topical delivery of therapeutic agents in the treatment of inflammatory bowel disease(a review)
- 5)Treatment of inflammatory bowel disease: a review of medical therapy(a review)
- 6)Budesonide Multi-matrix for the Treatment of Patients with Ulcerative Colitis (a review)
PubMed Literature
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