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CAS RN: 5638-76-6 | Product Number: B6621
Betahistine
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Purity: >98.0%(GC)(T)
Chemical Substance Law (ENCS):
5-3699
Synonyms:
- 2-(2-Methylaminoethyl)pyridine
- N-Methyl-2-(2-pyridinyl)ethanamine
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
¥9,500
|
10 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 25G |
¥33,200
|
13 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | B6621 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__8H__1__2N__2 = 136.20 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 5638-76-6 |
| Reaxys Registry Number | 112294 |
| MDL Number | MFCD00006362 |
Specifications
| Appearance | Colorless to Yellow to Orange clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 114 °C/30 mmHg |
| Flash point | 96 °C |
| Specific Gravity (20/20) | 0.99 |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| Chemical Substance Law (ENCS) |
5-3699 |
| Fire Defense Law | Group-4-3-III |
| RTECS# | UT5552000 |
Transport Information:
Application
Betahistine: A Histamine H1 Receptor Agonist/H3 Antagonist
Betahistine and its methanesulfonate [B1424] are structural analogs of histamine [H0146, dihydrochloride] that act as both partial histamine H1-receptor agonists and histamine H3 receptor antagonists in neuronal tissue. Betahistine increases histamine turnover and release by blocking presynaptic H3-receptors and inducing H3-receptor downregulation.1-3) Betahistine has been reported to increase vestibular blood flow and is used clinically as an antivertigo agent.2,3) Recently, it has been reported that betahistine induced the recall of forgotten memories in mice.4) (The product is for research use only.)
References
- 1) Actions of betahistine at histamine receptors in the brain
- 2) Betahistine increases vestibular blood flow
- 3) Histamine and betahistine in the treatment of vertigo: Elucidation of mechanisms of action (a review)
- 4) Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories
- 5) LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: application to a pharmacokinetic study in healthy volunteers
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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