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CAS RN: 50-63-5 | Product Number: C2301

Chloroquine Diphosphate

Purity: >98.0%(T)(HPLC)
Chemical Substance Law (ENCS):   9-279
  • N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate
  • 7-Chloro-4-[4-(diethylamino)-1-methylbutylamino]quinoline Diphosphate
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6   14   ≥40 
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This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number C2301
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__8H__2__6ClN__3·2H__3PO__4 = 515.86 
Physical State (20 deg.C) Solid
CAS RN 50-63-5
Reaxys Registry Number 4223142
PubChem Substance ID 87560990
SDBS (AIST Spectral DB) 52374
Merck Index (14) 2163
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 199 °C(dec.)
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
Chemical Substance Law (ENCS) 9-279
RTECS# VB2450000
Transport Information:
Exosome research


Chloroquine Diphosphate: A Derivative of 4-Aminoquinoline with Autophagy Inhibitory, Antimalarial and Anticancer Activities

Chloroquine diphosphate is a derivative of 4-aminoquinoline, which is an inhibitor of autophagy and has antimalarial and anticancer activities.1-3) In addition, chloroquine has been also reported to exert anti-corona viral activity, including anti-SARS-CoV-2, in vitro.4-6) The mechanism of action of chloroquine is not completely understood. But, some studies have demonstrated that chloroquine is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. In addition, while chloroquine can inhibit certain enzymes, its effect is believed to result, at least in part from its interaction with DNA. (The product is for research purpose only.)


Reagent for itching model


PubMed Literature

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