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CAS RN: 1910-42-5 | Product Number: D3685
1,1'-Dimethyl-4,4'-bipyridinium Dichloride
×
Purity: >98.0%(T)(HPLC)
Poisonous substance
|Chemical Substance Law (ENCS):
5-3722
Synonyms:
- Methyl Viologen
- Paraquat
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥6,000
|
3 | 15 | ≥60 | |
| 5G |
¥14,000
|
20 | 15 | ≥100 |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D3685 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__4Cl__2N__2 = 257.16 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1910-42-5 |
| Reaxys Registry Number | 3752782 |
| PubChem Substance ID | 87560498 |
| Merck Index (14) | 7031 |
| MDL Number | MFCD00011986 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Solubility in Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 180 °C |
| Boiling Point | 300 °C |
| Solubility in water | Soluble |
| Degree of solubility in water | 700 g/l 20 °C |
| Solubility (slightly sol. in) | Ethanol, Methanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H310 + H330 : Fatal in contact with skin or if inhaled. H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H373 : May cause damage to organs through prolonged or repeated exposure. H335 : May cause respiratory irritation. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust. P270 : Do not eat, drink or smoke when using this product. P262 : Do not get in eyes, on skin, or on clothing. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| Chemical Substance Law (ENCS) |
5-3722 |
| PRTR Law (New Specific Chemical) | Class 1 Designated Chemical Substances |
| Poisonous or Deleterious | Poisonous substance |
| RTECS# | DW2275000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | I |
Application
Mitophagy research
References
- Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- A critical role of superoxide anion in selenite-induced mitophagic cell death
Application
Reagent for pneumonitis (pulmonary fibrosis) model
References
- Pulmonary interstitial fibrosis from paraquat in the hamster
- C. Butler 2nd., Arch. Pathol. 1975, 99, 503.
- Paraquat lung injury in rabbits
- Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat
- A new model of diffuse interstitial pulmonary fibrosis in the rat
- Effectiveness of vitamin E and colchicine in amelioration of paraquat lung injuries using an experimental model
- E. Shahar, I. Keidar, E. Hertzeg, Z. Barzilay, Isr. J. Med. Sci. 1989, 25, 92.
- Anti-inflammatory effect of thalidomide in paraquat-induced pulmonary injury in mice
- Effect of pirfenidone on pulmonary fibrosis due to paraquat poisoning in rats
- Paraquat-induced pulmonary fibrosis starts at an early stage of inflammation in rats
Application
Reagents for Preparing Animal Disease Models
Reference
- Neuroprotective effects of polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice
Application
Reagent for Parkinson's disease model
References
- Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.
- Paraquat- and rotenone-induced models of Parkinson's disease.
PubMed Literature
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