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CAS RN: 143491-57-0 | Product Number: E1007

Emtricitabine


Purity: >98.0%(T)(HPLC)
Synonyms:
Documents:
25MG
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Product Number E1007
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__8H__1__0FN__3O__3S = 247.24  
Physical State (20 deg.C) Solid
CAS RN 143491-57-0
Reaxys Registry Number 5908714
PubChem Substance ID 253660241
Merck Index (14) 3565
MDL Number

MFCD00870151

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 153.0 to 157.0 °C
Specific rotation [a]20/D -137.0 to -143.0 deg(C=0.25, MeOH)
Properties (reference)
Melting Point 155 °C
Specific Rotation -140° (C=0.25,MeOH)
Maximum Absorption Wavelength 280(H2O) nm
Solubility in water Soluble
Degree of solubility in water 112 g/l   25 °C
Solubility (very soluble in) Methanol
GHS
Related Laws:
RTECS# UW7360500
Transport Information:
Application
Emtricitabine (FTC): a Nucleoside Reverse Transcriptase Inhibitor (NRTI)

Emtricitabine (FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus (HBV). FTC, after phosphorylated by cellular enzymes to emtricitabine 5'-triphosphate (FTC-TP), inhibits HIV and HBV reverse transcriptase (HIV-RT and HBV-RT).

References


PubMed Literature


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