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CAS RN: 490-46-0 | Product Number: E1226
(-)-Epicatechin
									 
							Purity: >97.0%(HPLC)
Synonyms:
						
						- (-)-cis-3,3',4',5,7-Pentahydroxyflavane
 
Product Documents:
                    
				
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					* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | E1226 | 
Purity / Analysis Method  
                                     | 
                                    >97.0%(HPLC) | 
| Molecular Formula / Molecular Weight | C__1__5H__1__4O__6 = 290.27 | 
| Physical State (20 deg.C) | Solid | 
Storage Temperature  
                                     | 
                                    Refrigerated (0-10°C) | 
| Store Under Inert Gas | Store under inert gas | 
| Condition to Avoid | Air Sensitive,Heat Sensitive | 
Packaging and Container  
                                     | 
                                    1G-Glass Bottle with Plastic Insert (View image) | 
| CAS RN | 490-46-0 | 
| Reaxys Registry Number | 92760 | 
| PubChem Substance ID | 468591690 | 
| MDL Number | MFCD00075648  | 
                                
Specifications
		  | Appearance | White to Light yellow to Light orange powder to crystal | 
| Purity(HPLC) | min. 97.0 area% | 
| Specific rotation [a]20/D | -56.0 to -64.0 deg(C=0.1, MeOH) | 
		Properties (reference)
	| Melting Point | 240 °C(dec.) | 
| Specific Rotation | -62° (C=0.1,MeOH) | 
| Maximum Absorption Wavelength | 280 nm (MeOH) | 
| Solubility (soluble in) | Methanol | 
 
						 GHS
						 | Pictogram | 
										   		 
								    			 | 
								   	 
| Signal Word | Warning | 
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation.  | 
                                
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention.  | 
                                
 
								 Related Laws: 
							   | RTECS# | K3745000 | 
 
						Transport Information:
							
			Application
		
			Efflux pump research
		
		(-)-Epicatechin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
 - Determination of Tea Components with Antioxidant Activity
 - Metabolism of green tea catechins: an overview
 - Green tea extract: Chemistry, antioxidant properties and food applications - A review
 - Antiviral effect of catechins in green tea on influenza virus
 - Green Tea: Nature's Defense against Malignancies (a review)
 - Biological functions of epicatechin: Plant cell to human cell health (a review)
 - (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
 - Metabolism of green tea catechins: an overview
 - Dietary flavonoids: Role of (-)-epicatechin and related procyanidins in cell signaling (a review)
 
			Application
		
			(-)-Epicatechin: A Components of Green Tea with a Variety of Biological Activities
		
		(-)-Epicatechin and (-)-epicatechin gallate [E0890] are major components of green tea which is the most popular beverages worldwide.  It has been reported that they possess a variety of biological activities, including antioxidant, anti-inflammatory, antiviral and anti-cancerous properties.  (The product is for research purpose only.)
References
			Application
		
			(-)-Epicatechin: An Antioxidant Flavonoid with Many Bioactive Properties
		
		(-)-Epicatechin is a flavan-3-ol, an antioxidant flavonoid that is present in green teas, red wine, cocoa products, and many fruits, such as apples.  It has demonstrated strong antioxidative, anti-inflammatory and anti-cancerous properties.  (The product is for research purpose only.)
References
Documents
Product Articles
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