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CAS RN: 99011-02-6 | Product Number: I0747
Imiquimod
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
- 4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
¥8,700
|
17 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 1G |
¥44,800
|
≥60 | 13 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | I0747 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__6N__4 = 240.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 99011-02-6 |
| Reaxys Registry Number | 7710060 |
| PubChem Substance ID | 87561300 |
| Merck Index (14) | 4922 |
| MDL Number | MFCD00866946 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 294 °C |
| Maximum Absorption Wavelength | 245 nm (H__2O/MeOH) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | NJ5903450 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
Application
Imiquimod: A Toll-Like Receptor (TLR) 7 Agonist and a Potent Immune Activator
Imiquimod is reported as a Toll-like receptor (TLR) 7 agonist and a potent immune activator. Imiquimod activates innate immune cells to produce interferon-α (IFN-α) and other cytokines both in vitro and in vivo. This immune-based mechanism provides activity against a number of viruses. In addition, it is also used for a reagent for inflammation and immunity disorder models. (The product is for research purpose only.)
References
- Imiquimod applied topically: a novel immune response modifier and new class of drug
- Imiquimod and resiquimod as novel immunomodulators
- Imiquimod and the imidazoquinolones: mechanism of action and therapeutic potential
- Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
- The antiviral activity of toll-like receptor 7 and 7/8 agonists
- Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
PubMed Literature
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Safety Data Sheet (SDS)
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Specifications
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