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CAS RN: 74103-07-4 | Product Number: K0053
Ketorolac Tromethamine
Purity: >98.0%(T)(HPLC)
Synonyms:
- Ketorolac Tris Salt
- (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid Tris Salt
Documents:
Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
---|---|---|---|---|
1G |
¥5,700
|
3 | 4 | 17 |
5G |
¥20,800
|
6 | 2 | Contact Us |
Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | K0053 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__5H__1__3NO__3·C__4H__1__1NO__3 = 376.41 |
Physical State (20 deg.C) | Solid |
CAS RN | 74103-07-4 |
Related CAS RN | 74103-06-3 |
Reaxys Registry Number | 6463165 |
PubChem Substance ID | 253661330 |
Merck Index (14) | 5306 |
MDL Number | MFCD00887595 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
Melting Point | 167 °C |
Maximum Absorption Wavelength | 322(MeOH) nm |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | UY7759900 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | III |
Application
Ketorolac Tromethamine: A Non-Selective Cyclooxygenase (COX) Inhibitor with Strong Analgesic Activity
Ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) with strong analgesic activity. Ketorolac is a non-selective cyclooxygenase (COX) inhibitor. Thus, it reduces prostaglandin synthesis. Ketorolac is the racemic mixture of (-)-S and (+)-R enantiomers. Most of its analgesic and COX inhibitory activity is retained in the S-isomer. Besides, some formulations for controlled release of ketorolac tromethamine have been reported. Ketorolac and its metabolites are excreted primarily by the kidneys. For your reference, [B4934] is used as a synthetic intermediate of ketorolac. (The product is for research purpose only.)
References
- The analgesic and anti-inflammatory profile of ketorolac and its tromethamine salt
- Ketorolac tromethamine absorption, distribution, metabolism, excretion, and pharmacokinetics in animals and humans
- Ketorolac. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential
- Semiinterpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine
- Ketorolac tromethamine formulations: an overview
- HPTLC determination of ketorolac tromethamine
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