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CAS RN: 71-58-9 | Product Number: M1964
Medroxyprogesterone Acetate
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Purity: >93.0%(GC)
Chemical Substance Law (ENCS):
9-1470
Synonyms:
- Medroxyprogesterone 17-Acetate
- 17α-Acetoxy-6α-methylprogesterone
- 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-Acetate
Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥4,200
|
2 | |||
| 5G |
¥12,800
|
≥40 | 16 | ≥40 |
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* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* For the case that without specific estimated shipping data, e.g.: If displayed as "will be shipped after 8 working days", the products will be shipped 8 working days later after ordering.
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 93.0 % |
| Melting point | 203.0 to 209.0 °C |
| Specific rotation [a]20/D | +45.0 to +51.0 deg(C=1, Dioxane) |
Properties (reference)
| Melting Point | 206 °C |
| Specific Rotation | 48° (C=1,Dioxane) |
| Solubility in water | Insoluble |
| Solubility (very soluble in) | Chloroform |
| Solubility (soluble in) | Dimethylformamide |
| Solubility (slightly sol. in) | Alcohol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| Chemical Substance Law (ENCS) |
9-1470 |
| RTECS# | TU5010000 |
Transport Information:
Application
Medroxyprogesterone acetate: Semi-Synthetic Progestational Agent
Medroxyprogesterone acetate (MPA) and megestrol acetate [M1949], semi-synthetic progestational agents, are effective hormonal treatments for metastatic breast cancer in postmenopausal women. The antineoplastic effect may result from inhibition of pituitary gonadotropin production and resultant decrease in estrogen secretion. In addition, MPA has the pregnancy maintaining effect and the anti-estrogen effect. (The product is for research purpose only.)
References
- Pregnancy Maintaining Effect of Synthetic Progestogens in the Rat
- Studies of the So-called Virilizing Effects of Steroids in Female Rat Fetuses
- Cytokine activity in cancer-related anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate (a review)
- The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer (a review)
- Determination of the residues of 50 anabolic hormones in muscle, milk and liver by very-high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry
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