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CAS RN: 57113-90-3 | Product Number: M2797
Methyl 2-(tert-Butoxycarbonylamino)-3-nitrobenzoate
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Purity: >98.0%(GC)
Synonyms:
- 2-(tert-Butoxycarbonylamino)-3-nitrobenzoic Acid Methyl Ester
- Methyl 2-(Boc-amino)-3-nitrobenzoate
- 2-(Boc-amino)-3-nitrobenzoic Acid Methyl Ester
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
¥10,300
|
4 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 25G |
¥35,400
|
It can be shipped in about 2-3 business days after ordering | 1 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | M2797 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__6N__2O__6 = 296.28 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 57113-90-3 |
| Reaxys Registry Number | 2887119 |
| PubChem Substance ID | 354334226 |
| MDL Number | MFCD06797690 |
Specifications
| Appearance | White to Yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 104.0 to 108.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 106 °C |
GHS
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Application
A Synthetic Intermediate of Azilsartan and Candesartan Cilexetil
This product is used for the synthesis of azilsartan [A2601]1,2) and candesartan cilexetil [C2635]2-4) which are angiotensin II type 1 receptor antagonist used mainly for the treatment of high blood pressure and congestive heart failure.
References
- An alternative synthesis of Azilsartan: an angiotensin II receptor blocker
- Synthesis and Characterization of Impurities of a Common and Advanced Intermediate of Candesartan and Azilsartan Antihypertensive Drugs
- Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of benzimidazolecarboxylic acids
- An efficient C-H arylation of a 5-phenyl-1H-tetrazole derivative: A practical synthesis of an angiotensin II receptor blocker
PubMed Literature
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