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CAS RN: 128607-22-7 | Product Number: O0441

Ospemifene


Purity: >98.0%(GC)
Synonyms:
Documents:
100MG
¥11,900

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1G
¥77,500
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Product Number O0441
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__2__4H__2__3ClO__2 = 378.90 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 128607-22-7
Reaxys Registry Number 10283864
PubChem Substance ID 253662436
MDL Number

MFCD00871890

Specifications
Appearance White to Almost white powder to crystal
Purity(GC) min. 98.0 %
Properties (reference)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
Transport Information:
Application
選択的エストロゲン受容体調節剤 (SERM),オスペミフェン

Ospemifene (FC1271a) was first reported as a metabolite of toremifene [T2832] which is an antiestrogen and a hormonal antitumor agent. Ospemifene is the first non-hormonal estrogen receptor agonist/antagonist or selective estrogen receptor modulator (SERM). It specifically binds to the estrogen receptor α and β with affinity closely similar to that of toremifene and tamoxifen [T2510]. Ospemifene is currently used for treatment of vulvovaginal atrophy (VVA). In addition, the antiestrogenic activity of ospemifene in several breast cancer animal models has been reported. (The product is for research purpose only.)

References


PubMed Literature


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