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CAS RN: 61-25-6 | Product Number: P0016
Papaverine Hydrochloride
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Purity: >99.0%(HPLC)
Chemical Substance Law (ENCS):
5-827
Synonyms:
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
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|---|---|---|---|---|---|
| 25G |
¥4,200
|
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P0016 |
Purity / Analysis Method 
|
>99.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__1NO__4·HCl = 375.85 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 61-25-6 |
| Reaxys Registry Number | 3921435 |
| PubChem Substance ID | 87574297 |
| Merck Index (14) | 7019 |
| MDL Number | MFCD00012745 |
Specifications
| Appearance | White powder to crystal |
| Purity(HPLC) | min. 99.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Solubility in Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 225 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| Chemical Substance Law (ENCS) |
5-827 |
| RTECS# | NW8575000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
Application
Papaverine Hydrochloride: An Isoquinoline Alkaloid with Smooth Muscle Relaxation Activity
Papaverine hydrochloride is an isoquinoline alkaloid obtained from opium or prepared synthetically. The most characteristic effect of papaverine is relaxation of the tonus of all smooth muscle. Pharmacological studies suggest that papaverine exerts its effect on by an inhibitory action on phosphodiesterase, resulting in increased intracellular cAMP as well as inhibition of voltage-gated calcium channels. (The product is for research purpose only.)
References
- Inhibition of cyclic-3',5'-nucleotide-phosphodiesterase as a possible mode of action of papaverine and similarly acting drugs
- Phosphodiesterase inhibitors
- On the mechanism of papaverine inhibition of the voltage-dependent Ca++ current in isolated smooth muscle cells from the guinea pig trachea
- Spectrophotometric determination of meclozine HCl and papaverine HCl in their pharmaceutical formulations
- Analytical profile of papaverine hydrochloride (a review on the desorption, physical properties, isolation, synthesis, biosynthesis, pharmacokinetics, stability, and determination of it)
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
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