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CAS RN: 29868-97-1 | Product Number: P2457
Pirenzepine Dihydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Dihydrochloride
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
¥7,700
|
2 | 3 | 13 | |
| 1G |
¥27,200
|
1 | 1 | 4 |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P2457 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__1N__5O__2·2HCl = 424.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 29868-97-1 |
| Related CAS RN
|
28797-61-7 |
| Reaxys Registry Number | 4732388 |
| PubChem Substance ID | 468592608 |
| Merck Index (14) | 7491 |
| MDL Number | MFCD00055214 |
Specifications
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Argentometric Titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 4.9 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 270 °C(dec.) |
| Solubility in water | Soluble |
| Solubility (slightly sol. in) | Methanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| RTECS# | UU7883000 |
Transport Information:
Application
Pirenzepine Dihydrochloride: A M1 Receptor Selective Antagonist
Pirenzepine dihydrochloride is a M1 receptor selective antagonist and a “selective” anti-ulcer agent. Unlike classic anticholinergic agents, pirenzepine inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions. (The product is for research purpose only.)
References
- Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases
- High performance liquid chromatographic determination of pirenzepine dihydrochloride in its pharmaceutical formulation
- Pirenzepine dihydrochloride (a review on the chemical detection method and pharmacology of it)
- HPLC determination of pirenzepine dihydrochloride in rabbit aqueous humor
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