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CAS RN: 100299-08-9 | Product Number: P2547

Pemirolast Potassium


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one Potassium Salt
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1G
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Product Number P2547
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__0H__7KN__6O = 266.31  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 100299-08-9
Related CAS RN 69372-19-6
Reaxys Registry Number 8097604
PubChem Substance ID 354334415
Merck Index (14) 7078
MDL Number

MFCD01690051

Specifications
Appearance Light yellow to Yellow to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 317 °C(dec.)
Solubility in water Soluble
Solubility (very slightly) Methanol
Solubility (insoluble in) Ethanol
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H361 : Suspected of damaging fertility or the unborn child.
H362 : May cause harm to breast-fed children.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P263 : Avoid contact during pregnancy/ while nursing.
P260 : Do not breathe dusts or mists.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# UV1164470
Transport Information:
Application
Pemirolast Potassium: A Water-Soluble Inhibitor of Type I Allergy

Pemirolast potassium is a water-soluble inhibitor of type I allergy. Pharmacological studies indicate that it suppresses the formation of 1,2-diacylglycerol and phosphatidic acid, and the decrease in phosphatidylinositol (PI). It also can stabilize the cell membrane of mast cells, inhibit the inflow and release of Ca2+, inhibit the activation of phosphodiesterase and increase the intracellular cAMP levels. Recently, some laboratory animal studies reported that it can reduce chemotherapy-induced nausea and vomiting. (The product is for research purpose only.)

References


PubMed Literature


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