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CAS RN: 6533-68-2 | Product Number: S0021

Scopolamine Hydrobromide Trihydrate


Purity: >98.0%(T)(HPLC)
Synonyms:
Documents:
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Product Number S0021
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__2__1NO__4·HBr·3H__2O = 438.32  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 6533-68-2
Related CAS RN 114-49-8&51-34-3
Reaxys Registry Number 6100669
PubChem Substance ID 87575651
Merck Index (14) 8406
MDL Number

MFCD00012647

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %(after drying)
Specific rotation [a]20/D -24.0 to -27.0 deg(C=5, H2O)(after drying)
Solubility in Water almost transparency
Drying loss max. 13.0 %
Properties (reference)
Melting Point 195 °C
Specific Rotation -25.5° (C=5,H2O)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# YM4550000
Transport Information:
UN Number UN1544
Class 6.1
Packing Group III
Application
Scopolamine Hydrobromide: A Belladonna Alkaloid with Anticholinergic Activity

Scopolamine salts ([S0021][ S0230] and [S0231]) and N-oxide [S0229], belladonna alkaloids, are anticholinergic agents. Their free base, scopolamine competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine [A0754] as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al. (The product is for research purpose only.)

References


Application
Reagent for experimental amnesia (Alzheimer's disease) model

References


PubMed Literature


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