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CAS RN: 112665-43-7 | Product Number: S0943

Seratrodast


Purity: >98.0%(T)(HPLC)
Synonyms:
Documents:
100MG
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Product Number S0943
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__2H__2__6O__4 = 354.45 
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
Packaging and Container 100MG-Glass Bottle with Plastic Insert (View image)
CAS RN 112665-43-7
Reaxys Registry Number 6489593
PubChem Substance ID 253662316
Merck Index (14) 8459
MDL Number

MFCD00875701

Specifications
Appearance Light yellow to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 128 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# DA1600050
Transport Information:
Application
Seratrodast: A Thromboxane-A2 (TXA2) Receptor Antagonist

Seratrodast (AA-2414) is the first thromboxane-A2 (TXA2) receptor antagonist. TXA2, a metabolite of arachidonic acid [A0781], promotes platelet aggregation and vessel constriction, and is released by platelets when these are activated by local tissue damage. Seratrodast, a TXA2 receptor antagonist, reduces bronchial hyperresponsiveness in asthmatic subjects. Seratrodast undergoes cytochrome P450 (CYP) dependent primary metabolism to a major (5-methylhydroxy seratrodast) and a minor (4-hydroxy seratrodast) metabolite. (The product is for research purpose only.)

References


PubMed Literature


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