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CAS RN: 491-67-8 | Product Number: T2721
Baicalein
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Purity: >98.0%(T)
Synonyms:
- 5,6,7-Trihydroxyflavone
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥12,800
|
3 | 9 | ≥40 | |
| 5G |
¥41,100
|
10 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T2721 |
Purity / Analysis Method 
|
>98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__0O__5 = 270.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 491-67-8 |
| Reaxys Registry Number | 272683 |
| PubChem Substance ID | 125307744 |
| Merck Index (14) | 942 |
| MDL Number | MFCD00017459 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 265 °C |
| Solubility (soluble in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | DJ3100898 |
Transport Information:
Application
Efflux pump research
Baicalein has been reported to inhibit TetK tetracycline efflux pump.1) The compound also showed synergy with tetracycline in a MRSA strain that doesn’t possess tetK, or with β-lactams.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Remarkable Synergies between Baicalein and Tetracycline, and Baicalein and β-Lactams against Methicillin-Resistant Staphylococcus aureus
- Baicalein Inhibits Staphylococcus aureus Biofilm Formation and the Quorum Sensing System In Vitro
- Virtual screening for novel quorum sensing inhibitors to eradicate biofilm formation of Pseudomonas aeruginosa
- Biological properties of baicalein in cardiovascular system (a review)
- New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin (a review)
- Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders (a review)
Application
Quorum sensing research / Biofilm research
References
Application
Baicalein: A Flavonoid with Various Pharmacological Activities Including Antioxidant and Anti-Tumor Activities
Baicalein is a flavonoid and one of the major constituent of the root of Scutellaria baicalensis, as well as wogonin [W0010] and baicalin [B2835]. Baicalein possesses a multitude of pharmacological activities. It has been reported that baicalein is a potent free radical scavenger and xanthine oxidase inhibitor, thus improving endothelial function and conferring cardiovascular protective actions against oxidative stress-induced cell injury. Furthermore, baicalein has potent anti- inflammatory and anti-tumor activities. Baicalein is cytotoxic to various human tumor cell lines in vitro and inhibit tumor growth in vivo. (The product is for research purpose only.)
References
PubMed Literature
Documents
Product Articles
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Specifications
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