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CAS RN: 2398-96-1 | Product Number: T3059
Tolnaftate
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Purity: >97.0%(HPLC)(N)
Chemical Substance Law (ENCS):
4-1110
Synonyms:
- O-2-Naphthyl Methyl(3-methylphenyl)carbamothioate
- Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥6,500
|
15 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 5G |
¥22,600
|
4 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T3059 |
Purity / Analysis Method 
|
>97.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__9H__1__7NOS = 307.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 2398-96-1 |
| Reaxys Registry Number | 2752620 |
| PubChem Substance ID | 253661582 |
| Merck Index (14) | 9519 |
| MDL Number | MFCD00056611 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(with Total Nitrogen) | min. 97.0 % |
| Melting point | 111.0 to 115.0 °C |
Properties (reference)
| Melting Point | 113 °C |
| Maximum Absorption Wavelength | 258 nm (MeOH) |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Ether |
GHS
Related Laws:
| Chemical Substance Law (ENCS) |
4-1110 |
| RTECS# | FD8891300 |
Transport Information:
Application
Tolnaftate: A Synthetic Antifungal Reagent
Tolnaftate is a chemical synthetic antifungal reagent. Although the exact mechanism of action is not entirely known, tolnaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane.
References
- The mode of antifungal action of tolnaftate
- Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate
- Tolnaftate (a review)
- Spectrophotometric methods for the determination of tolnaftate
- Analysis of some antifungal drugs by spectrophotometric and spectrofluorimetric methods in different pharmaceutical dosage forms
PubMed Literature
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Specifications
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