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CAS RN: 35607-66-0 | Product Number: C3598
Cefoxitin
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Purity: >98.0%(HPLC)
Synonyms:
- (6R,7S)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩224,300
|
20 | 13 | Contact Us | |
| 5G |
₩748,800
|
7 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C3598 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__7N__3O__7S__2 = 427.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 35607-66-0 |
| Reaxys Registry Number | 4216947 |
| PubChem Substance ID | 468591185 |
| Merck Index (14) | 1936 |
| MDL Number | MFCD00072014 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
Properties (reference)
| Melting Point | 127 °C(dec.) |
| Solubility (soluble in) | Dimethylformamide |
| Solubility (insoluble in) | Ether, Chloroform |
GHS
Related Laws:
| RTECS# | XI0386500 |
Transport Information:
| H.S.code* | 2941.90-000 |
Application
Cefoxitin: A Second Generation Cephem Antibiotic against beta-Lactamase
Cefoxitin and its sodium salt [C3602] are semi-synthetic antibiotic that are derived from cephamycin C which is produced by Streptomyces lactamdurans. Cefoxitins have bactericidal activity against a wide range of Gram-negative and Gram-positive bacteria including aerobes and anaerobes.1-3) Cefoxitins are second generation cephem antibiotics which act by inhibition bacterial cell wall synthesis. Due to the presence of a 7-α methoxy group in the β-lactam ring, cefoxitins exhibit a high degree of stability in the presence of beta-lactamases. In addition, cefoxitin disk diffusion method has been used for the tests for routine detection of all classes of MRSA.4,5)
References
- 1) Cefoxitin, a semi-synthetic cephamycin: a microbiological overview (a review)
- 2) Cefoxitin and cephamycins: microbiological studies (a review)
- 3) Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use
- 4) Evaluation of three techniques for detection of low-level methicillin-resistant Staphylococcus aureus (MRSA): a disk diffusion method with cefoxitin and moxalactam, the Vitek 2 system, and the MRSA-screen latex agglutination test
- 5) Results of disk diffusion testing with cefoxitin correlate with presence of mecA in Staphylococcus spp.
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