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CAS RN: 33419-42-0 | Product Number: E0675
Etoposide

Purity: >98.0%(HPLC)
Synonyms:
- 4'-Demethylepipodophyllotoxin 9-(4,6-O-Ethylidene-β-D-glucopyranoside)
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
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---|---|---|---|---|---|
100MG |
₩72,200
|
21 | 0 | It can be shipped in about 2 weeks after ordering | |
1G |
₩447,700
|
17 | 1 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | E0675 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__9H__3__2O__1__3 = 588.56 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Condition to Avoid | Light Sensitive |
Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 33419-42-0 |
Reaxys Registry Number | 365969 |
PubChem Substance ID | 87558799 |
Merck Index (14) | 3886 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Water | max. 7.0 % |
Properties (reference)
Melting Point | 251 °C |
Solubility (slightly sol. in) | Ethanol |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H302 : Harmful if swallowed. H360 : May damage fertility or the unborn child. H362 : May cause harm to breast-fed children. H371 : May cause damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H340 : May cause genetic defects. H350 : May cause cancer. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | KC0190000 |
Transport Information:
H.S.code* | 2938.90-000 |
Application
Adeno-associated virus vector transduction enhancer
Etoposide exhibits enhancement of adeno-associated virus transduction.1)
References
- 1) Identification and validation of small molecules that enhance recombinant adeno-associated virus transduction following high-throughput screens
Application
Etoposide: A Topoisomerase-II Inhibitor
Etoposide (VP 16) is a semisynthetic antitumor alkaloid which is synthesized form podophyllotoxin [P1771] , a toxin found in the American Mayapple. Etoposide interferes with DNA synthesis by inhibiting the enzyme topoisomerase-II. In order to prevent and correct of topological problems caused by the DNA double helix, topoisomerase-II catalyzes the relaxation of negatively supercoiled DNA, the knotting and unknotting DNA and the linking complementary rings of single-stranded DNA into double-stranded rings. Then the inhibition action leads to cell cycle arrest at G2/M, apoptosis or cell death. Bacterial type II topoisomerases (DNA gyrase and Topoisomerase-IV) are the targets of quinolone antibiotics.
References
- Etoposide: four decades of development of a topoisomerase II inhibitor(a review)
- Etoposide, topoisomerase II and cancer(a review)
- Plants as a source of anti-cancer agents(a review)
- DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs(a review)
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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