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CAS RN: 66575-29-9 | Product Number: F0855
Forskolin
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Purity: >95.0%(HPLC)
Synonyms:
- Coleonol
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 10MG |
₩ 105,600
|
4 | ≥20 |
| 50MG |
₩ 363,200
|
18 | 19 |
* Please contact our distributor of SEJIN CI
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 224.0 to 228.0 °C |
Properties (reference)
| Melting Point | 225 °C |
| Specific Rotation | -17° |
| Maximum Absorption Wavelength | 305 nm |
GHS
Related Laws:
| RTECS# | QL6150000 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Forskolin: A Diterpene Activator of Cyclic AMP-Generating Systems
Forskolin (also called Coleonol) is a diterpene that is produced by the Indian Coleus plant (Coleus forskohlii). Forskolin directly activates adenylyl cyclase (AC) and raises 3',5'-cyclic AMP (cAMP) levels in a wide variety of cell types. AC catalyzes the conversion of ATP to cAMP and pyrophosphate. cAMP is an important second messenger important in many biological processes.
References
- Forskolin: Unique diterpene activator of adenylate cyclase in membranes and in intact cells
- Forskolin: its biological and chemical properties (a review)
- K. B. Seamon, J. W. Daly, Adv. Cyclic Nucleotide Protein Phosphorylation Res. 1986, 20, 1.
- Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action? (a rview)
- Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis
- Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling (a review)
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