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CAS RN: 480-19-3 | Product Number: I1068
Isorhamnetin
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Purity: >95.0%(HPLC)
Synonyms:
- 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
- 3'-Methoxy-3,4',5,7-tetrahydroxyflavone
- 3'-Methylquercetin
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
₩230,100
|
≥60 | ≥80 | Contact Us | |
| 50MG |
₩803,400
|
≥40 | 11 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | I1068 |
Purity / Analysis Method 
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__2O__7 = 316.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 480-19-3 |
| Reaxys Registry Number | 44723 |
| PubChem Substance ID | 468592077 |
| MDL Number | MFCD00017310 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
Properties (reference)
| Maximum Absorption Wavelength | 370 nm (MeOH) |
GHS
Related Laws:
| RTECS# | LK9275450 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Efflux pump research
Isorhamnetin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
- Effect of naturally occurring flavonoids on lipid peroxidation and membrane permeability transition in mitochondria
- Antioxidant activity and phenolic compounds in 32 selected herbs
- Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production inactivated macrophages
- O-methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation
- In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells
- Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD
Application
Isorhamnetin: A 3'-O-Methylated Flavonoid with Biological Activities
Isorhamnetin is a natural 3'-O-methylated flavonoid (3’-O-methylated quercetin [P0042]) that occurs in fruits and medicinal herbs. It has been investigated in its antioxidant1,2) and anti-inflammatory3,4) activity, and its influence on human cancer cells.5) (The product is for research purpose only.)
References
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