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CAS RN: 142273-20-9 | Product Number: K0052
Kenpaullone
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Purity: >97.0%(HPLC)
Synonyms:
- 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 10MG |
₩ 204,800
|
11 | 9 |
| 50MG |
₩ 660,800
|
7 | 15 |
* Please contact our distributor of SEJIN CI
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
| Product Number | K0052 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__1BrN__2O = 327.18 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | <0°C |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 142273-20-9 |
| Reaxys Registry Number | 5346108 |
| PubChem Substance ID | 253661159 |
| MDL Number | MFCD02683595 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Elemental analysis(Nitrogen) | 8.00 to 9.00 % |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.79-000 |
Application
Kenpaullone: A Potent CDKs and GSK-3β Inhibitor
Kenpaullone is a potent ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3β (GSK-3β). In addition, kenpaullone can functionally replace Kruppel-like factor 4 (Klf4), which is a Yamanaka factors, in reprogramming induction.
References
- The specificities of protein kinase inhibitors: an update
- The selectivity of protein kinase inhibitors: a further update
- Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity
- Small molecule GSK-3 inhibitors increase neurogenesis of human neural progenitor cells
- Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4
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