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CAS RN: 93793-83-0 | Product Number: R0178
Roxatidine Acetate Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-Acetoxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
₩56,600
|
1 | 12 | Contact Us | |
| 1G |
₩202,800
|
5 | 3 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | R0178 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__8N__2O__4·HCl = 384.90 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 93793-83-0 |
| Reaxys Registry Number | 5915111 |
| PubChem Substance ID | 253661076 |
| Merck Index (14) | 8274 |
| MDL Number | MFCD00941429 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 146.0 to 150.0 °C |
Properties (reference)
| Melting Point | 148 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | AC3855000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Roxatidine Acetate Hydrochloride: A Specific and Competitive H2-Receptor Antagonist
Roxatidine acetate hydrochloride is a specific and competitive H2-receptor antagonist. Roxatidine acetate and its main metabolite roxatidine inhibit histamine-induced gastric acid secretion with a potency greater than that of cimetidine [C1252] and ranitidine [R0073]. In addition, H2-receptor antagonists such as roxatidine acetate and cimetidine are known to suppress the growth of several tumors including gastrointestinal cancer by reducing vascular endothelial growth factor (VEGF) expression.
References
- A review of the animal pharmacology of roxatidine acetate
- Roxatidine- and cimetidine-induced angiogenesis inhibition suppresses growth of colon cancer implants in syngeneic
- Roxatidine suppresses inflammatory responses via inhibition of NF-κB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages
- Determination of roxatidine in human plasma by liquid chromatography/electrospray mass spectrometry and application to a clinical pharmacokinetic study
PubMed Literature
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