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CAS RN: 4345-03-3 | Product Number: T2628
D-α-Tocopherol Succinate
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Purity: >97.0%(GC)(T)
Synonyms:
- Vitamin E Succinate
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 5G |
₩70,400
|
7 | ≥20 |
| 25G |
₩224,000
|
18 | ≥20 |
* Please contact our distributor of SEJIN CI
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
| Product Number | T2628 |
| Purity / Analysis Method | >97.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__3__3H__5__4O__5 = 530.79 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | 0-10°C |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 4345-03-3 |
| Reaxys Registry Number | 65995 |
| PubChem Substance ID | 253661999 |
| Merck Index (14) | 9495 |
| MDL Number | MFCD00072055 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 97.0 % |
| Purity(Neutralization titration) | min. 97.0 % |
| Melting point | 73.0 to 77.0 °C |
| Specific rotation [a]20/D | +3.0 to +5.0 deg(C=8, EtOH) |
Properties (reference)
| Melting Point | 75 °C |
| Specific Rotation | 4° (C=8,EtOH) |
| Maximum Absorption Wavelength | 286(EtOH) nm |
| Solubility in water | Insoluble |
| Solubility (very soluble in) | Chloroform,Acetone,Ether |
| Solubility (very slightly) | Methanol |
GHS
Related Laws:
| RTECS# | EJ9984000 |
Transport Information:
| H.S.code* | 2936.28-000 |
Application
α-Tocopheryl Succinate (α-TOS): an ester of Vitamin E with various biological activities
Vitamin E [T0251] is an antioxidant that protects organism from damage caused by free radicals. In contrast, α-tocopheryl succinate (α-TOS), an ester of Vitamin E, lacks antioxidative ability. Recently, α-TOS comes into focus due to its various biological activities such as induction of apoptosis and activation of protein kinase C.
References
- Inhibition of cell proliferation by α-tocopherol. Role of protein kinase C
- Induction of cancer cell apoptosis by α-tocopheryl succinate: molecular pathways and structural requirements
- Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo
- Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumour activity (a review)
- Vitamin E analogues and immune response in cancer treatment (a review)
PubMed Literature
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