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CAS RN: 147127-20-6 | Product Number: T3006
Tenofovir
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (R)-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩154,100
|
13 | ≥100 | Contact Us | |
| 5G |
₩501,200
|
7 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | T3006 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__9H__1__4N__5O__4P = 287.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 147127-20-6 |
| Reaxys Registry Number | 7415378 |
| PubChem Substance ID | 253660231 |
| Merck Index (14) | 9146 |
| MDL Number | MFCD00943794 |
Specifications
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0%(calcd.on anh.substance) |
| Specific rotation [a]20/D | -19.0 to -21.0 deg(C=1, 0.1mol/L HCl)(calcd.on anh.substance) |
| Water | max. 6.0 % |
Properties (reference)
| Melting Point | 283 °C |
| Specific Rotation | -20° (C=1,0.1mol/L HCl) |
GHS
Related Laws:
| RTECS# | SZ6563600 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Tenofovir: a Nucleotide Reverse Transcriptase (RT) Inhibitor
Tenofovir, also known as PMPA, is a nucleotide reverse transcriptase (RT) inhibitor. It shows activity against hepatitis B virus (HBV) and human immunodeficiency virus (HIV). It is the active metabolite of tenofovir disoproxil fumarate.
References
- Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine
- Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors
- Phosphonomethoxyalkyl analogs of nucleotides
- Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections
- Case history: Acyclic nucleoside phosphonates: a key class of antiviral drugs
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