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CAS RN: 150915-40-5 | Product Number: T3640
Tirofiban Hydrochloride Monohydrate
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Purity: >98.0%(HPLC)
Synonyms:
- N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine Hydrochloride Monohydrate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
₩454,400
|
2 | 3 | Contact Us | |
| 250MG |
₩1,587,300
|
4 | 4 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | T3640 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__3__6N__2O__5S·HCl·H__2O = 495.08 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 150915-40-5 |
| Related CAS RN | 144494-65-5&142373-60-2 |
| Reaxys Registry Number | 14636978 |
| PubChem Substance ID | 354335596 |
| Merck Index (14) | 9464 |
| MDL Number | MFCD07368623 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 5.00 to 6.00 % |
| Specific rotation [a]20/D | -12.0 to -16.0 deg(C=1, MeOH) |
| Water | 3.1 to 4.1 % |
Properties (reference)
| Melting Point | 132 °C |
| Specific Rotation | -14° (C=1,MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2935.90-000 |
Application
Tirofiban Hydrochloride: A Nonpeptide Glycoprotein IIb/IIIa Receptor Antagonist
Tirofiban hydrochloride is a reversible antagonist of fibrinogen binding to the platelet glycoprotein (GP) IIb/IIIa receptor, the major platelet surface receptor. GP IIb/IIIa plays a major role in the regulation of platelet adhesion and aggregation during hemostasis, and the GP IIb/IIIa receptor has been identified as the pivotal mediator of platelet aggregation. Therefore, tirofiban hydrochloride specifically inhibits fibrinogen-dependent platelet aggregation and prolongs bleeding times. (The product is for research purpose only.)
References
- Tirofiban: an investigational platelet glycoprotein IIb/IIIa receptor antagonist (a review)
- Glycoprotein IIb/IIIa integrin blockade
- In vitro and in vivo studies on the metabolism of tirofiban
- Integrin αIIbβ3: From Discovery to Efficacious Therapeutic Target
- Determination of Tirofiban in human serum by liquid chromatography-tandem mass spectrometry
- Validated spectrofluorimetric methods for the determination of apixaban and tirofiban hydrochloride in pharmaceutical formulations
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