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Useful Pd(II) Catalyst for Cross Coupling
Reactions
No.105(June 2001)
Palladium compound 1 catalyzes the cross coupling reaction of acid chlorides with tetraorganotin compounds to give ketones under mild conditions and in high yields1). The reaction is tolerant of a wide variety of functional groups both on the acid chloride and the tin reagent, thus making this reaction a useful method for ketone synthesis. Palladium compound 1 is an excellent catalyst, giving higher reaction yields and shorter reaction times than other palladium catalysts.
References
- 1)Cross coupling reactions with acyl chlorides and Organostannane compounds
- 2)Review: The Stille reaction
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