Maintenance Notice (5:15 AM - 4:55 PM May 24, 2025): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.198
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 58479-61-1 | Product Number: B1223
tert-Butyldiphenylchlorosilane
×
![]()
×
Purity: >97.0%(GC)
Synonyms:
- tert-Butylchlorodiphenylsilane
- TBDPSCl
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5ML |
€20.00
|
7 | ≥60 |
|
| 25ML |
€61.00
|
≥40 | ≥100 |
|
| 100ML |
€243.00
|
10 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B1223 |
| Purity / Analysis Method | >97.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__9ClSi = 274.86 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Moisture Sensitive |
| CAS RN | 58479-61-1 |
| Reaxys Registry Number | 644023 |
| PubChem Substance ID | 87564159 |
| SDBS (AIST Spectral DB) | 12630 |
| MDL Number | MFCD00000497 |
Specifications
| Appearance | Colorless to Light orange to Yellow clear liquid |
| Purity(GC) | min. 97.0 % |
Properties (reference)
| Boiling Point | 125 °C/0.06 mmHg |
| Flash point | 112 °C |
| Specific Gravity (20/20) | 1.07 |
| Refractive Index | 1.57 |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H314 : Causes severe skin burns and eye damage. H290 : May be corrosive to metals. |
| Precautionary Statements | P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P390 : Absorb spillage to prevent material damage. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 261-282-0 |
Transport Information:
| UN Number | UN2987 |
| Class | 8 |
| Packing Group | II |
| HS Number | 2931900090 |
Application
TCI Practical Example: TBDPS Protection Reaction of the Alkyl Alcohol
-
Used Chemicals
-
Procedure
-
To a mixture of 2,3-O-Isopropylidene-D-ribonic γ-Lactone (13.2 g, 70.0 mmol) and imidazole (10.0 g, 147 mmol) in DMF (100 mL) at r.t. was added dropwise TBDPSCl (18.0 mL, 70.0 mmol). The reaction mixture was stirred at r.t. for 20 h, and then poured into ice water. The aqueous solution layer was extracted by diethyl ether. The organic layer was dried over Na2SO4 and concentrated under reduced pressure, and recrystallized from hexane to give 5-O-tert-butyldiphenylsilyl-2,3-O-isopropylidene-D-ribono-1,4-lactone (22.1 g, 74% yield) as a white solid.
-
Experimenter’s Comments
-
The reaction mixture was monitored by TLC (hexane:ethyl acetate= 4:1, Rf = 0.5) and 1H NMR.
-
Analytical Data
-
1H NMR (400 MHz, CDCl3); δ 7.61-7.58 (m, 4H), 7.48-7.37 (m, 6H) , 4.88 (d, 1H, J = 5.2 Hz), 4.79 (d, 1H, J = 6.0 Hz), 4.56 (s, 1H), 3.89 (dd, 1H, J = 2.0, 11.2 Hz), 3.73 (d, 1H, J = 11.2 Hz), 1.47 (s, 3H), 1.38 (s, 3H), 1.02 (s, 9H).
-
Lead Reference
-
- Chiral 1,4-dicarbonyl-2,3-O-isopropylidene derivatives. Rapid racemization on standing
PubMed Literature
Articles/Brochures
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.