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CAS RN: 93703-24-3 | Product Number: B4134
8-Bromo-3-methylxanthine
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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| Product Number | B4134 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__6H__5BrN__4O__2 = 245.04 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 93703-24-3 |
| Reaxys Registry Number | 4691271 |
| PubChem Substance ID | 354333161 |
| MDL Number | MFCD17676400 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 300 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
A Synthetic Intermediate of Bioactive Xanthine Derivatives
This compound is used for a synthetic intermediate of bioactive xanthine derivatives such as DPP-4 inhibitors and tyrosine kinase inhibitors.
References
- 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes
- Structure-Based Optimization of Potent and Selective Inhibitors of the Tyrosine Kinase Erythropoietin Producing Human Hepatocellular Carcinoma Receptor B4 (EphB4)
- 1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases
- Optimization of Inhibitors of the Tyrosine Kinase EphB4. 2. Cellular Potency Improvement and Binding Mode Validation by X-ray Crystallography
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