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CAS RN: 154361-50-9 | Product Number: C2878


Purity: >98.0%(T)(HPLC)
  • 5'-Deoxy-5-fluoro-N4-[(pentyloxy)carbonyl]cytidine
5   4  
≥20  ≥20 

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* The storage conditions are subject to change without notice.

Product Number C2878
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__5H__2__2FN__3O__6 = 359.35  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 154361-50-9
Reaxys Registry Number 8583270
PubChem Substance ID 253661933
Merck Index (14) 1754
MDL Number


Properties (reference)
Melting Point 123 °C(dec.)
Specific Rotation 98° (C=1,MeOH)
Solubility in water Slightly soluble
Degree of solubility in water 26 g/l   20 °C
Solubility (very soluble in) Ethanol,Methanol
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H360 : May damage fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# HA3852500
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Capecitabine: A Prodrug of 5-fluorouracil (5-FU) [F0151] for Selective Delivery to Tumor

Capecitabine is a prodrug of antitumor antimetabolite, metabolized to the active form 5-fluorouracil (5-FU) [F0151] by three enzymes located in the liver and in tumors. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine [D4342] and 5'-deoxy-5-fluorouridine (doxifluridine) [D3579], to form 5-FU. Capecitabine and its intermediary metabolites are not cytotoxic by themselves. The final step (doxifluridine to 5-FU) requires thymidine phosphorylase (dThdPase) that is significantly more active in tumor than normal tissue. This tumor-selective delivery of 5-FU ensured greater efficacy and a more favorable safety profile than with other fluoropyrimidines. (The product is for research purpose only.)


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