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CAS RN: 56796-39-5 | Product Number: C3029
Cefmetazole Sodium Salt
×
Purity: >92.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
$71.00
|
1 | 0 | It can be shipped in about 2 weeks after ordering | |
| 1G |
$216.00
|
7 | 0 | It can be shipped in about 2 weeks after ordering |
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* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C3029 |
Purity / Analysis Method 
|
>92.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__6N__7NaO__5S__3 = 493.51 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 56796-39-5 |
| Related CAS RN
|
56796-20-4 |
| Reaxys Registry Number | 5403925 |
| PubChem Substance ID | 253660567 |
| Merck Index (14) | 1926 |
| MDL Number | MFCD00214260 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 92.0 area% |
| Purity(Ion exchange titration) | min. 97.0 % |
| Specific rotation [a]20/D | +73.0 to +85.0 deg(C=1, H2O) |
| NMR | confirm to structure |
Properties (reference)
| Specific Rotation | 80° (C=1,H2O) |
| Solubility (soluble in) | Acetone |
| Solubility (insoluble in) | Chloroform, Tetrahydrofuran |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | XI0372200 |
Transport Information:
| H.S.code* | 2941.90-000 |
Application
Cefmetazole Sodium Salt: A (7S)-Methoxy Cephalosporin (Cephamycin)
Cefmetazole sodium salt (CS-1170), a first generation of (7S)-methoxy cephalosporin (cephamycin), is chemically synthesized form 7-MAC [M2129]. The steric hindrance effect that is enhanced by introducing (7S)-methoxy into the β-lactam ring significantly increases the stability of β-lactam antibiotics against β-lactamases, and to some extent reduces the problems of bacterial drug-resistance. Cefmetazole has a broad spectrum of activity against Gram-negative and Gram-positive bacteria, and is generally more active against Gram-negative bacteria than the ‘first and second generation’ cephalosporins.
References
- Antibacterial activity of cefmetazole alone and in combination with fosfomycin against methicillin- and cephem-resistant Staphylococcus aureus
- Annual incidence, epidemiology, and comparative in vitro susceptibilities to cefoxitin, cefotetan, cefmetazole, and ceftizoxime of recent community-acquired isolates of the Bacteroides fragilis group.
- Enhanced rectal absorption of cefmetazole and cefoxitin in the presence of epinephrine metabolites in rats and a high-performance liquid chromatographic assay for cephamycin antibiotics
- Review of the in-vitro spectrum and characteristics of cefmetazole (CS-1170)
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