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CAS RN: 123171-59-5 | Product Number: C3565
Cefepime Dihydrochloride Monohydrate
New
Purity: >95.0%(T)(HPLC)
Synonyms:
- (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Dihydrochloride Monohydrate
Product Documents:
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| 1G |
$109.00
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| Product Number | C3565 |
Purity / Analysis Method
|
>95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__4N__6O__5S__2·2HCl·H__2O = 571.49 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Hygroscopic,Heat Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 123171-59-5 |
| Reaxys Registry Number | 30196632 |
| MDL Number | MFCD01687679 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Precipitation Titration) | min. 95.0 % |
| Specific rotation | +39.0 to +47.0 deg(C=0.3, water) |
| Water | 3.0 to 4.5 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2941.90-000 |
Application
Cefepime: A Fourth-Generation Cephalosporin Antibacterial Agent
Cefepime (dihydrochloride monohydrate) is a fourth-generation cephalosporin that acts by inhibiting bacterial cell wall synthesis. In common with other β-lactam agents, cefepime exerts its antibacterial effects by binding to penicillin-binding proteins (PBPs). Cefepime exhibits broad-spectrum in vitro activity against a wide range of Gram-positive and Gram-negative bacteria. Cefepime is highly resistant to hydrolysis by most beta-lactamases and rapidly penetrates Gram-negative bacterial cells. (The product is for research use only.)
References
- Cefepime: A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
- Cefepime: a reappraisal in an era of increasing antimicrobial resistance (a review)
- Clinical Pharmacokinetics and Pharmacodynamics of Cefepime (a review)
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