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CAS RN: 51146-56-6 | Product Number: I0549
(S)-(+)-Ibuprofen
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Purity: >98.0%(GC)(T)
Synonyms:
- (S)-2-(4-Isobutylphenyl)propanoic Acid
- S-(+)-p-Isobutylhydratropic Acid
- (+)-α-Methyl-4-(2-methylpropyl)benzeneacetic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€32.00
|
2 | 25 |
|
|
| 5G |
€100.00
|
Ships within 2 weeks after ordering | 20 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | I0549 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__3H__1__8O__2 = 206.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 51146-56-6 |
| Reaxys Registry Number | 3590020 |
| PubChem Substance ID | 87571895 |
| SDBS (AIST Spectral DB) | 41004 |
| MDL Number | MFCD00069289 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Optical purity(GC) | min. 98.0 ee% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 51.0 to 55.0 °C |
| Solubility in Methanol | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 52 °C |
| Specific Rotation | 59° (C=2,EtOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2916399070 |
Application
S-(+)-Ibuprofen: The Pharmacologically Active Enantiomer of Ibuprofen
S-(+)-Ibuprofen is the pharmacologically active enantiomer of ibuprofen [I0415], a non-selective non-steroidal anti-inflammatory drug (NSAID). It works by inhibiting both the COX-1 and COX-2 enzymes and prostaglandin synthesis. (The product is for research purpose only.)
References
- Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (-)-isomer
- Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C
- Characterization of the protein binding of chiral drugs by high-performance affinity chromatography. Interactions of R- and S-ibuprofen with human serum albumin
- Enantioselective pharmacokinetics of ibuprofen and involved mechanisms (a review)
- S+ Ibuprofen (dexibuprofen): the superior non steroidal anti-inflammatory agents for development of pharmaceuticals (a review)
- Resolution of enantiomers of ibuprofen by liquid chromatography: a review
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