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Published TCIMAIL newest issue No.201
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CAS RN: 603-00-9 | Product Number: H1430
Proxyphylline
×
Purity: >98.0%(HPLC)(N)
Synonyms:
- 7-(2-Hydroxypropyl)-1,3-dimethylxanthine
- 7-(2-Hydroxypropyl)theophylline
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
€ 37,00
|
1 | 11 |
|
|
| 25G |
€ 120,00
|
1 | 10 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | H1430 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4N__4O__3 = 238.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 603-00-9 |
| Reaxys Registry Number | 262773 |
| PubChem Substance ID | 253660319 |
| Merck Index (14) | 7905 |
| MDL Number | MFCD00022833 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 134.0 to 138.0 °C |
Properties (reference)
| Melting Point | 136 °C |
| Solubility (soluble in) | Ethanol |
| Solubility (slightly sol. in) | Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 210-028-7 |
| RTECS# | XH5907500 |
Transport Information:
| HS Number | 2939590000 |
Application
Proxyphylline: A Water-Soluble Derivative of Theophylline
Proxyphylline, which is a water-soluble 7-hydroxylpropyl derivative of theophylline [T0179], that acts as a cardiac stimulant, vasodilator and bronchodilator. (The product is for research purpose only.)
References
- Comparative studies on new water-soluble derivatives of theobromine and theophylline
- R. Taugner, M. v. Bubnoff, H. Weth, H. Waltz, H. Hochrein, M. Bartels, E. Schmidt, F. Raff, J. Tzoumertis,
O. Hammrich, et al., Arzneimittelforschung 1956, 6, 601.
- R. Taugner, M. v. Bubnoff, H. Weth, H. Waltz, H. Hochrein, M. Bartels, E. Schmidt, F. Raff, J. Tzoumertis,
- Hydroxypropyl theophylline: a pharmacological comparison with other theophylline preparations
- The action of new derivatives of theophylline and theobromine on the contraction of the heart muscle
- G. Kuschinsky, E. Muscholl, Arzneimittelforschung 1958, 8, 14.
- Pharmacokinetics of proxyphylline in adults after intravenous and oral administration
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