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CAS RN: | 产品编码: A2509
Anti-Sialyl Lewis A Monoclonal Antibody (2D3)
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Product Information
Volume/Quantity: 0.1 mg/vial
Product Form: Purified mouse monoclonal antibody/IgM, κ-chain
Buffer: Phosphate buffered-saline(-) ((PBS(-))
Preparation: The antibody is purified from ascites fluid.
Preservative: 0.05% sodium azide
Stabilizer: None
Immunogen: Immunized with human colon cancer cells (Colo201), and screened using sialyl Lewis A-active glycolipids
Specificity: Sialyl Lewis A antigen
Clone Name: 2D3
Applications
Immunohistochemistry, flow-cytometric analysis, ELISA, TLC-immunostaining, Western blotting, cell adhesion inhibition experiments.
Storage
Store at -20 ºC to -80 ºC (Preferably at -80 ºC). It is not recommended storing at 4 ºC. Avoid repeated freezing and thawing.
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| 产品编码 | A2509 |
| 外观与形状（20°C） | 液体 |
储存温度 
|
冷冻 (-80°C) |
| 应避免的情况 | 加热 |
技术规格
| Appearance | Colorless to Almost colorless clear liquid |
| Titer(ELISA) | to pass test |
物性（参考值）
GHS
相关法规
运输信息
| HS编码* | 3504.00-000 |
应用
Anti-Sialyl Lewis A Monoclonal Antibody (2D3)
References
- Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A
- Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages
- K. Zenita, K. Hirashima, K. Shigeta, N. Hiraiwa, A. Takada, K. Hashimoto, E. Fujimoto, K. Yago, R. Kannagi, J. Immunol. 1990, 144, 4442-4451.
- Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium
- A. Takada, K. Ohmori, T. Yoneda, K. Tsuyuoka, A. Hasegawa, M. Kiso, R. Kannagi, Cancer Res. 1993, 53, 354-361.
- Importance of E-selectin (ELAM-1) and sialyl Lewisa in the adhesion of pancreatic carcinoma cells to activated endothelium
- Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates
- Clinical application of functional glycoproteomics - dissection of glycotopes carried by soluble CD44 variantsin sera of patients with cancers
- Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors, siglec-7 and -9
- K. Miyazaki, K. Sakuma, Y. I. Kawamura, M. Izawa, K. Ohmori, M. Mitsuki, T. Yamaji, Y. Hashimoto, A. Suzuki, Y. Saito, T. Dohi, R. Kannagi, J. Immunol. 2012, 188, 4690-4700.
- Peritoneal colonization by human pancreatic cancer cells is inhibited by antisense FUT3 sequence
- Detection of ligands for selectins in the oligosaccharide fraction of human milk
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