Maintenance Notice (3:15 AM - 2:55 PM May 24, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Materials Science News May 2025 | [Product Highlights] Endogenous Biotin-Blocking Reagent... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
请选择数量
CAS RN: 147-94-4 | 产品编码: C2035
Cytarabine
×
![]()
×
补充产品信息:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| 产品编码 | C2035 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__9H__1__3N__3O__5 = 243.22 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 147-94-4 |
| 相关CAS RN | 69-74-9 |
| Reaxys-RN | 89175 |
| PubChem物质ID | 87558791 |
| Merck Index (14) | 2784 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +155.0 to +162.0 deg(C=1, H2O) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 214 °C |
| 比旋光度 [α]D | 158° (C=1,H2O) |
| 最大吸收波长 | 272 nm (H__2O) |
| 水溶性 | 可溶 |
GHS
相关法规
| RTECS# | HA5425000 |
运输信息
| HS编码* | 2934.99-000 |
应用
Cytarabine (ara-C): D-Arabinosyl Nucleoside exhibiting Anti-Leukemia and Anti-DNA Virus Activities
Certain D-arabinosyl nucleosides, notably cytarabine (ara-C) and vidarabine (ara-A) [V0098] are used as an anti-leukemia agent and an anti-DNA virus agent. Ara-C and ara-A are cell cycle phase-specific antineoplastic agents, affecting cells only during the S-phase of cell division. Intracellularly, ara-C and ara-A are converted into the 5-triphosphates (ara-CTP and ara-ATP), which are the active metabolites. The mechanism of actions are not completely understood, but it appear that ara-CTP and ara-ATP act through the inhibition of tumor cell or virus-induced DNA polymerases, competing with dCTP and dATP, respectively. Incorporation of them into DNA and RNA also contribute to their cytotoxicity. (The product is for research purpose only.)
References
- The mechanisms of lethal action of arabinosyl cytosine (araC) and arabinosyl adenine (araA) (a review)
- Ara-C: cellular and molecular pharmacology (a review)
- Acute Myeloid Leukemia (a review)
参考文献
文档
技术文章
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。