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CAS RN: 152121-30-7 | 产品编码: F0870
SB 202190
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纯度/分析方法: >95.0%(HPLC)
别名：
- 4-(4-氟苯基)-2-(4-羟苯基)-5-(4-吡啶基)-1H-咪唑
- 4-[4-(4-氟苯基)-5-(吡啶-4-基)-1H-咪唑-2-基]苯酚
- 4-[4-(4-氟苯基)-5-(4-吡啶基)-1H-咪唑-2-基]苯酚
- 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole
- 4-[4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
- 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
产品文档：
| 产品编码 | F0870 |
| 纯度/分析方法 | >95.0%(HPLC) |
| 分子式/分子量 | C__2__0H__1__4FN__3O = 331.35 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,加热 |
| CAS RN | 152121-30-7 |
| Reaxys-RN | 7654810 |
| MDL编号 | MFCD00941964 |
技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 215 °C |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | SL4584000 |
运输信息
| HS编码* | 2933.39-000 |
应用
SB 202190: A Selective Inhibitor of p38 MAPK
SB 202190 is a selective inhibitor of p38 MAP kinase (mitogen-activated protein kinase, MAPK), a serine/threonine-specific protein kinase. SB 202190 has been reported to induce apoptosis. (The product is for research purpose only.)
References
- Characterization of the structure and function of a new mitogen-activated protein kinase (p38β)
- Specificity and mechanism of action of some commonly used protein kinase inhibitors
- Induction of apoptosis by SB202190 through inhibition of p38β mitogen-activated protein kinase
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