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CAS RN: 5451-09-2 | 產品號碼: A0325
5-Aminolevulinic Acid Hydrochloride

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產品號碼 | A0325 |
純度/分析方法 ![]() |
>98.0%(T) |
分子式 / 分子量 | C__5H__9NO__3·HCl = 167.59 |
外觀與形狀(20°C) | Solid |
儲存條件 ![]() |
Room Temperature (Recommended in a cool and dark place, <15°C) |
儲存在惰性氣體下 | Store under inert gas |
應避免的情況 | Light Sensitive,Hygroscopic |
包裝和容器 ![]() |
100MG-Glass Bottle with Plastic Insert (閲覽圖片), 1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 5451-09-2 |
相關CAS RN ![]() |
106-60-5 |
Reaxys-RN | 3690651 |
PubChem Substance ID | 87561977 |
SDBS (AIST Spectral DB) | 4767 |
Merck Index(14) | 446 |
MDL編號 | MFCD00012869 |
產品規格
Appearance | White to Orange to Green powder to crystal |
Purity(Argentometric Titration) | min. 98.0 % |
Solubility in Water | almost transparency |
性質
水溶性 | Soluble |
GHS
圖形表示 |
![]() |
信號詞 | Warning |
危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
RTECS # | OI1640000 |
運輸資料
HS編碼* | 2922.50-000 |
Application
5-Aminolevulinic acid (5-ALA): A Diagnostic Agent for Tumors Tissue
5-Aminolevulinic acid (5-ALA), a natural biochemical precursor of heme, is metabolized in a series of enzymatic reactions to fluorescent protoporphirin IX (PpIX) in the course of heme synthesis. 5-ALA is preferentially taken up by tumour tissue and intracellularly metabolised to PpIX which accumulates in tumor cells. Following excitation with blue light (λ=400 to 410 nm), the PpIX, which has accumulated selectively in the malignant tissue, emits a strong red PplX fluorescence (the peak is at 635 nm). Therefore, 5-ALA is often used to visualize tumorous tissue. (The product is for research purpose only.)
References
- Photosensitization of murine tumor, vasculature and skin by 5-aminolevulinic acid-induced porphyrin
- Prodrugs of 5-aminolevulinic acid for photodynamic therapy
- 5-aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells
- 5-Aminolevulinic acid-based photodynamic therapy: clinical research and future challenges (a review)
- The stability of 5-aminolevulinic acid in solution
- Liquid chromatography assay for 5-aminolevulinic acid: Application to in vitro assessment of skin penetration via Dermaportation
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