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CAS RN: 497-76-7 | 產品號碼: A0522
| 產品號碼 | A0522 |
純度/分析方法 
|
>95.0%(HPLC) |
| 分子式 / 分子量 | C__1__2H__1__6O__7 = 272.25 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Hygroscopic |
| CAS RN | 497-76-7 |
| Reaxys-RN | 89673 |
| PubChem Substance ID | 87562130 |
| SDBS (AIST Spectral DB) | 10908 |
| Merck Index(14) | 773 |
| MDL編號 | MFCD00016915 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 197.0 to 202.0 °C |
| Specific rotation [a]20/D | -63.0 to -68.0 deg(C=4, H2O)(calcd.on anh.substance) |
| Solubility in Water | very faint turbidity |
| Water | max. 3.0 % |
性質
| 熔點 | 198 °C |
| 比旋光 [α]D | -65.5° (C=4,H2O) |
| 水溶性 | Soluble |
| 溶解性（可溶於） | Alcohol |
GHS
相關法規
| RTECS # | CE8863000 |
運輸資料
| HS編碼* | 2938.90-000 |
Application
Arbutin: A Competitive Inhibitor of Tyrosinase
Arbutin (β-arbutin) is a hydroquinone glycoside, which is accumulated in many plant species such as bearberry (Arctostaphylos uva-ursi L.), bergenia (Bergenia spp.) and myrothamnus (Myrothamnus flabellifolia Welw.). It has been reported that arbutine inhibits the oxidation of L-tyrosine in a competitive manner catalyzed by tyrosinase which is an oxidase that catalyzes the rate-limiting step in melanin (a group of natural pigments) biosynthesis. Arbutins (α- and β-arbutins) are widely used in the cosmetic industry. (Related product: α-arbutin [A3284]) (The product is for research purpose only.)
References
- Arbutin: mechanism of its depigmenting action in human melanocyte culture
- Effects of α- and β-arbutin on activity of tyrosinases from mushroom and mouse melanoma
- Survey and mechanism of skin depigmenting and lightening agents (a review)
- Biotechnological production of arbutins (α- and β-arbutins), skin-lightening agents, and their derivatives (a review)
- Analyses of arbutin and chlorogenic acid, the major phenolic constituents in Oriental pear
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