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CAS RN: 464-92-6 | 產品號碼: A2475
| 產品號碼 | A2475 |
純度/分析方法 
|
>97.0%(T) |
| 分子式 / 分子量 | C__3__0H__4__8O__5 = 488.71 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器
|
200MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 464-92-6 |
| PubChem Substance ID | 468590113 |
| MDL編號 | MFCD00238541 |
產品規格
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Specific rotation [a]20/D | +47.0 to +52.0 deg(C=0.1, MeOH) |
| NMR | confirm to structure |
性質
| 熔點 | 318 °C(dec.) |
| 比旋光 [α]D | 50.3° (C=0.25,MeOH) |
GHS
| 危險性說明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相關法規
| RTECS # | YU9580000 |
運輸資料
| HS編碼* | 2918.19-000 |
Application
Asiatic Acid: A Pentacyclic Triterpene Possess Wide Pharmacological Activities
Asiatic acid is a pentacyclic triterpene extracted from Centella asiatica which is a tropical medicinal plant native to India, Sri Lanka, Madagascar, South Africa, Indonesia, and Malaysia. Asiatic acid possess wide pharmacological activities, and has been widely used in Indian traditional Ayurvedic medicine. In recent years, more and more studies have been reported about the pharmacological activities, clinical application and structure modification of asiatic acid. (The product is for research purpose only.)
References
- Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells
- Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells
- Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: Possible involvement of the IKK and MAPK pathways
- Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban (a review)
- Centella asiatica in food and beverage applications and its potential antioxidant and neuroprotective effect (a review)
- Determination of biologically active constituents in Centella asiatica
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