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CAS RN: 68401-81-0 | 產品號碼: C2622
補充產品訊息:
This product has not been tested for potency and is guaranteed for chemical purity.
| 產品號碼 | C2622 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__3H__1__3N__5O__5S__2 = 383.40 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 68401-81-0 |
| Reaxys-RN | 5777502 |
| PubChem Substance ID | 160870913 |
| Merck Index(14) | 1951 |
| MDL編號 | MFCD00072000 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +135.0 to +145.0 deg(C=1、0.1mol/LNaOH3mL+H2O7mL) |
| NMR | confirm to structure |
性質
| 熔點 | 227 °C(dec.) |
| 比旋光 [α]D | 139° (C=1,0.1mol/L NaOH 3mL+H2O 7mL) |
GHS
相關法規
| RTECS # | XI0367375 |
運輸資料
| HS編碼* | 2941.90-000 |
Application
Ceftizoxime: A Third Generation Semisynthetic Cephalosporin Antibiotic
Ceftizoxime is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-amino-3-nor-3-cephalosporanic acid. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, and is generally more active against Gram-negative bacteria than the first and second generation cephalosporins.
References
- Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin
- Ceftizoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
- Ceftizoxime and other third-generation cephalosporins: structure-activity relationships
- Activities of beta-lactam antibiotics against Escherichia coli strains producing extended-spectrum beta-lactamases
- Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney
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