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CAS RN: 66592-87-8 | 產品號碼: C3951
Cefadroxil Monohydrate
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| 產品號碼 | C3951 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__6H__1__7N__3O__5S·H__2O = 381.41 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Hygroscopic |
| CAS RN | 66592-87-8 |
| Reaxys-RN | 5694571 |
| MDL編號 | MFCD01682047 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Water | 4.0 to 6.0 % |
| Specific rotation | +165 to +178 deg(C=1,water)(calcd.on anh.substance) |
| NMR | confirm to structure |
性質
| 水溶性 | Slightly soluble |
| 溶解性（不溶於） | Ethanol |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2941.90-000 |
Application
Cefadroxil: A Semisynthetic Cephalosporin against a Wide Range of Gram-Positive and Gram-Negative Bacteria
Cefadroxil, a semisynthetic cephalosporin, is active against a wide range of Gram-positive and Gram-negative bacteria. It inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin-binding proteins (PBPs). The result is the formation of a defective, osmotically unstable cell wall and bacterial cell lysis (bactericidal effect). It is an oral cephalosporin similar in structure and spectrum of antibacterial activity to cephalexin [C2248] and cephradine [C2988], but with different pharmacokinetic properties. Not only does cefadroxil have a longer serum half-life, but it is virtually unaffected by concurrent food intake. (The product is for research purpose only.)
References
- Cefadroxil, a new broad-spectrum cephalosporin
- Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine
- Selective spectrophotometric determination of phenolic β-lactam antibiotics in pure forms and in their pharmaceutical formulations
- Characteristics, Properties and Analytical Methods of Cefadroxil: A Review
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