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CAS RN: 28611-39-4 | 產品號碼: D4428
4-(Dimethylamino)phenylboronic Acid (contains varying amounts of Anhydride)
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* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
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洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | D4428 |
| 分子式 / 分子量 | C__8H__1__2BNO__2 = 165.00 |
| 外觀與形狀（20°C） | Solid |
儲存條件 
|
Frozen (<0°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic,Heat Sensitive |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 28611-39-4 |
| Reaxys-RN | 3118297 |
| PubChem Substance ID | 253660318 |
| MDL編號 | MFCD01074642 |
產品規格
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(Neutralization titration) | 97.0 to 113.0 % |
性質
| 熔點 | 227 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2931.90-000 |
Application
TCI Practical Example: Regioselective Silylation of an Unprotected Carbohydrate Using the Boronic Acid and the Phosphine Oxide
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Used Chemicals
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Procedure
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To a solution of methyl α-L-fucopyranoside (356 mg, 2 mmol), 4-(dimethylamino)phenylboronic acid (66 mg, 0.4 mmol, 0.2 equiv), tributylphosphine oxide (87 mg, 0.2 mmol, 0.2 equiv) and DIPEA (517 mg, 0.68 mL, 4.0 mmol, 2.0 equiv) in acetonitrile (10 mL) was added TBDPSCl (1.10 g, 1.03 mL, 4.0 mmol, 2.0 equiv) at rt and the mixture was stirred at 60 °C. After 24 h, methanol (1 mL) was added to the reaction mixture and the solvent was removed under reduced pressure. The residue was purified by column chromatography (ethyl acetate:hexane = 0:1 - 1:1 on silica gel) to give 1 as a colorless oil (510 mg，y. 61%).
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Experimenter’s Comments
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The reaction mixture was monitored by TLC (ethyl acetate:hexane = 1:1, Rf = 0.59).
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Analytical Data
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Compound 1
1H NMR (400 MHz, CDCl3); δ 7.75-7.67 (m, 4H), 7.48-7.36 (m, 6H), 4.68 (d, 1H, J = 3.2 Hz), 3.93-3.80 (m, 2H), 3.68 (brq, 1H, J = 6.5 Hz), 3.44-3.43 (m, 1H), 3.29 (s, 3H), 2.55 (brs, 1H), 1.53 (d, 1H, J = 8.9 Hz), 1.22 (d, 3H, J = 6.8 Hz), 1.10 (s, 9H).
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Lead Reference
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- Regioselective silylation of pyranosides using a boronic acid / Lewis base co-catalyst system
考研文獻
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）