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CAS RN: 152628-02-9 | 產品號碼: D5079
1,7'-Dimethyl-2'-propyl-2,5'-bibenzimidazole
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產品規格
| Appearance | White to Light yellow to Light orange powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 130 °C(dec.) |
| 溶解性（可溶於） | Methanol |
GHS
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
A Key Synthetic Intermediate of Telmisartan
This product has been used as a key synthetic intermediate of telmisartan [T2861] which is an angiotensin II receptor type 1 (AT1) antagonist.
References
- An Efficient and Impurity-Free Process for Telmisartan: An Antihypertensive Drug
- Synthesis and biological activities of novel nonpeptide angiotensin II receptor antagonists based on benzimidazole derivatives bearing a heterocyclic ring
- Design, Synthesis, and Docking Studies of Novel Benzimidazoles for the Treatment of Metabolic Syndrome
- Stability-indicating HPLC method for simultaneous estimation of low level impurities of telmisartan and hydrochlorothiazide in tablet dosage forms
- AQbD-Oriented Development of a New LC Method for Simultaneous Determination of Telmisartan and Its Impurities
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