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CAS RN: 36923-21-4 | 產品號碼: D5234
Diphenylmethyl 7β-Amino-3-cephem-4-carboxylate
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純度/分析方法: >98.0%(HPLC)
别名:
- Benzhydryl (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Benzhydryl Ester
- 7β-Amino-3-cephem-4-carboxylic Acid Diphenylmethyl Ester
文件：
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產品規格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 164.0 to 168.0 °C |
| Specific rotation [a]20/D | +50.0 to +55.0 deg(C=1, CHCL3) |
性質
| 熔點 | 166 °C |
| 比旋光 [α]D | 53° (C=1,CHCl3) |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2934.99-000 |
Application
A Key Building Block for Semisynthetic Cephalosporin Antibiotics
This product is used as a key building block for semisynthetic cephalosporin antibiotics, such as ceftibuten [C3391].
References
- Synthesis and biological properties of 7β-[(Z)-2-(2-amino-4-thiazolyl)-4-carboxy-2-butenoylamino]-3-cephem-4-carboxylic acid (7432-S), a new oral cephem antibiotic
- Synthesis and structural-activity relationships of 7β-[(Z)-2-(2-aminothiazol-4-yl)-3-(substituted)-2-propenoylamino[-3-desacetoxymethylcephalosporins
- Studies on new catechol containing cephalosporins. II. Synthesis and structure-activity relationships of cephalosporins having a catechol moiety at the C-7 position
- The synthesis and evaluation of 2-substituted-7-(alkylidene)cephalosporin sulfones as β-lactamase inhibitors
- Ceftibuten: Development of a Commercial Process Based on Cephalosporin C. Part III. Process for the Conversion of 3-Exomethylene-7(R)-glutaroylaminocepham-4-carboxylic Acid 1(S)-Oxide to Ceftibuten
考研文獻
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