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CAS RN: 244767-67-7 | 產品號碼: D6168
| 產品號碼 | D6168 |
純度/分析方法 
|
>97.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__0H__1__9N__5 = 329.41 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 244767-67-7 |
| Reaxys-RN | 8934631 |
| MDL編號 | MFCD09833899 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 216.0 to 220.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 218 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
運輸資料
| HS編碼* | 2933.59-000 |
Application
Dapivirine: A Potent Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
Dapivirine (TMC 120) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV type 1 (HIV-1) reverse transcriptase (RT), an essential viral enzyme that transcribes viral RNA into DNA. (The product is for research purpose only.)
References
- In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides
- Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide
- Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor
- The development and validation of an UHPLC-MS/MS method for the rapid quantification of the antiretroviral agent dapivirine dapivirine in human plasma
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