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CAS RN: 1257-08-5 | 產品號碼: E0890
(-)-Epicatechin Gallate
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| 產品號碼 | E0890 |
純度/分析方法
|
>98.0%(HPLC) |
| 分子式 / 分子量 | C__2__2H__1__8O__1__0 = 442.38 |
| 外觀與形狀(20°C) | Solid |
儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
包裝和容器
|
100MG-Glass Bottle with Plastic Insert (閲覽圖片), 20MG-Glass Bottle with Plastic Insert (閲覽圖片) |
| CAS RN | 1257-08-5 |
| Reaxys-RN | 65603 |
| PubChem Substance ID | 135727012 |
| MDL編號 | MFCD00075936 |
產品規格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -175.0 to -187.0 deg(C=1, EtOH) |
性質
| 熔點 | 255 °C |
| 比旋光 [α]D | -177° (C=1,EtOH) |
GHS
相關法規
| RTECS # | DH9030000 |
運輸資料
| HS編碼* | 2932.99-000 |
Application
Gingipain inhibitor
Catechin derivatives, which included (-)-epigallocatechin gallate, (-)-epicatechin gallate, (-)-gallocatechin gallate, and (-)-catechin gallate, have been reported to inhibit Arg-gingipain (Rgp) in Porphyromonas gingivalis.1) The 50% inhibitory concentrations (IC50s) of these catechin derivatives for Rgp ranged from 3 to 5 μM. (-)-Epicatechin gallate is one of these derivatives. The compound was also shown to inhibit Lys-gingipain (Kgp), although weaker than Rgp.2)
(The product is for research purpose only.)
(The product is for research purpose only.)
References
- 1) Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis
- 2) Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids
- Determination of Tea Components with Antioxidant Activity
- Metabolism of green tea catechins: an overview
- Green tea extract: Chemistry, antioxidant properties and food applications - A review
- Antiviral effect of catechins in green tea on influenza virus
- Green Tea: Nature's Defense against Malignancies (a review)
- Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate
- Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes
- Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate
- Antioxidant properties of polyphenols extracted from green and black teas
Application
(-)-Epicatechin Gallate: A Components of Green Tea with a Variety of Biological Activities
(-)-Epicatechin gallate and (-)-epicatechin [E1226] are major components of green tea which is the most popular beverages worldwide. It has been reported that they possess a variety of biological activities, including antioxidant, anti-inflammatory, antiviral and anti-cancerous properties. (The product is for research purpose only.)
References
Application
Study of Componenst of Tea Polyphenols
References
PubMed Literature
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